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Best of South America with Amazon Cruise Santiago → Iquitos (2025)

23 days
From Santiago to Iquitos
4.1
26 traveler reviews

No departure dates available

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Plan your adventure:
Explorer
Curated to ignite your sense of adventure
Fully Guided
An experienced guide will be with you for the entire tour
Low Intensity
Travelers can expect some light physical activities
Guided in English
Group Size 1 - 200
Ages 8+
Image of a map showing the route of the tour

Highlights

  • Explore vibrant Valparaiso and local vineyards
  • Discover Buenos Aires and visit La Recoleta Cemetery
  • Experience the majestic Iguazu Falls by train
  • Tour Machu Picchu with a local guide
  • Cruise the Amazon and explore its rich ecosystem

Itinerary

View Full Itinerary
  1. Introduction
  1. Day 1 Arrive Santiago
  2. Day 2 Santiago, Valparaíso
  3. Day 3 Santiago
  4. Day 4 Santiago, Buenos Aires
  5. Day 5 Buenos Aires
  6. Day 6 Buenos Aires
  7. Day 7 Buenos Aires, Iguazú Falls
  8. Day 8 Iguazú Falls
  9. Day 9 Iguazú Falls, Rio de Janeiro
  10. Day 10 Rio de Janeiro
  11. Day 11 Rio de Janeiro
  12. Day 12 Rio de Janeiro, Lima
  13. Day 13 Lima
  14. Day 14 Lima, Sacred Valley
  15. Day 15 Sacred Valley, Maras, Moray
  16. Day 16 Sacred Valley, Machu Picchu
  17. Day 17 Machu Picchu, Cusco
  18. Day 18 Cusco
  19. Day 19 Cusco, Lima, Iquitos, Amazon Cruise
  20. Day 20 Amazon Cruise
  21. Day 21 Amazon Cruise
  22. Day 22 Amazon Cruise
  23. Day 23 Amazon Cruise, Depart Iquitos
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What's Included

Expand All
  • Accommodation
  • Guide
  • Meals
  • Additional Services
  • Transport
  • Free eSIM
    TourRadar offers the lead traveler (the person who booked) a free 1GB eSIM for the trip. The eSIM is redeemable only through the TourRadar app 72 hours before departure.

What's Not Included

  • Flights
  • Insurance
  • Optional
  • Additional Services

Where You'll Stay

All accommodations are subject to change

Operated by

APT

Number of tours

372

Age Range

8 to 99 years old

Response time

within 1 day

Response rate

67%

A family-owned company since its conception in the 1920s. APT had its...

Read more

Your Peace of Mind Options

Cancellation Policy

A transparent overview of applicable fees.

Travel Insurance

Be covered for any unforseen circumstances.

Reviews About This Operator

Can’t find the answer to your question?
Reach out to the experts at APT with your enquiry, they usually respond within 1 day.

No departure dates available

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Plan your adventure:

Good to Know

Tour ID: 271108

  • Currencies
    $
    Argentine Peso
    Argentina
    R$
    Brazilian Real
    Brazil
    $
    Chilean Peso
    Chile
    $
    US Dollar
    Ecuador
    S/.
    Sol
    Peru
  • Plugs & Adapters

    As a traveler from New Zealand you will need an adaptor for type L.

    Type I
    Argentina
    Type L
    Chile
  • Vaccines
    • These are only indications, so please visit your doctor before you travel to be 100% sure.
    • Typhoid - Recommended for Argentina.Brazil.Chile.Ecuador.Peru. Ideally 2 weeks before travel.
    • Hepatitis A - Recommended for Argentina.Brazil.Chile.Ecuador.Peru. Ideally 2 weeks before travel.
    • Hepatitis B - Recommended for Argentina.Brazil.Chile.Ecuador.Peru. Ideally 2 months before travel.
    • Rabies - Recommended for Argentina.Chile.Ecuador.Peru. Ideally 1 month before travel.
    • Yellow fever - Recommended for Argentina.Brazil.Ecuador.Peru. Ideally 10 days before travel.
    • Tuberculosis - Recommended for Brazil.Ecuador.Peru. Ideally 3 months before travel.
  • Visa
    • Unfortunately we cannot offer you a visa application service. Whether you need a visa or not depends on your nationality and where you wish to travel. Assuming your home country does not have a visa agreement with the country you're planning to visit, you will need to apply for a visa in advance of your scheduled departure.
    • Here is an indication for which countries you might need a visa. Please contact the local embassy for help applying for visas to these places.
  • Payment information
    • For any tour departing before April 13th, 2026 a full payment is necessary. For tours departing after April 13th, 2026, a minimum payment of $1,100 is required to confirm your booking with APT. The final payment will be automatically charged to your credit card on the designated due date. The final payment of the remaining balance is required at least 120 days prior to the departure date of your tour. TourRadar never charges you a booking fee and will charge you in the stated currency.
    • The following cards are accepted for "APT" tours: Visa, Maestro, Mastercard, American Express or PayPal. TourRadar does NOT charge you an extra fee for using any of these payment methods.
  • Cancellation Policy
  • Accessibility
    Some tours are not suitable for mobility-restricted traveler, however, some operators may be able to accommodate special requests. For any enquiries, you can contact our customer support team, who are ready and waiting to help you.

Who is travelling?

AdultsAges 18 or above

2

ChildrenUnder 18

0

Select departure month

2025

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec

2026

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec

2027

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec