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Best of South America with Amazon Cruise Santiago → Iquitos (2026)

22 days
From Santiago to Iquitos
4.1
26 traveler reviews
From
NZ $27,895 per person
+ $5,400 additional upfront costs

Price based on Cheapest Room

Price based on Shared Room

Price based on Private Single Room

Price based on Private Double Room

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2026

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2027

Jan
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1 Adult2 Adults, 1 Child2 Children

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Plan your adventure:
Explorer
Curated to ignite your sense of adventure
Fully Guided
An experienced guide will be with you for the entire tour
Medium Intensity
Travelers should be comfortable with somewhat-demanding activities
Guided in English
Group Size 1 - 200
Ages 8+
Image of a map showing the route of the tour

Itinerary

  1. Day 1

    Santiago

    You'll arrive in Santiago and head to your hotel to settle in. This evening you're joining a welcome dinner with fellow travelers and your tour director, so you'll get to know the group right away.

    Meals
    Dinner (Welcome dinner)
    Accommodation
    Hotel (Santiago)

    Included Activities

    • Welcome dinner
    Itinerary Image 1
  2. Day 2

    Santiago to Valparaíso to Santiago

    Today you're traveling to Valparaiso on the coast. The city's known for its colorful clifside houses and strong art scene. You'll walk through the historic quarter, take a funicular ride for views of the vibrant buildings and port, then have lunch at a local vineyard before heading back to Santiago.

    Meals
    Lunch (Lunch at a local vineyard)
    Accommodation
    Hotel (Santiago)

    Included Activities

    • Guided discovery of Valparaíso historic quarter
    • Funicular ride with views of Valparaíso
    Landmarks
    Valparaíso Historic Quarter
  3. Day 3

    Santiago

    A guided tour takes you through Chile's capital this morning, with views of the snow-capped Andes and Pacific in the distance. After that, you have the afternoon free to explore on your own. For dinner, you'll choose from two featured restaurants in the city.

    Accommodation
    Hotel (Santiago)

    Included Activities

    • Guided discovery of Santiago

    Optional Activities

    • Dinner at Liguria Lastarria - Traditional Chilean dishes including empanadas, tuna tartar and Chilean-style pichanga, accompanied by cocktails, wine and beer
    • Dinner at Ambrosia - Chef Carolina Bazán's fusion of Chilean and French cuisine featuring ceviche in an elegant, relaxed atmosphere
    Landmarks
    Andes Mountains
  4. Day 4

    Santiago to Buenos Aires

    You're flying to Buenos Aires today. After transferring to your hotel in the upscale Recoleta district, you'll see the area's beautiful parks and grand mansions. Later in the evening, you'll catch a tango demonstration and try some authentic tapas to get a feel for local culture.

    Meals
    Dinner (Tango demonstration and tapas)
    Accommodation
    Hotel (Buenos Aires)

    Included Activities

    • Tango demonstration and tapas
    Landmarks
    Recoleta
    Itinerary Image 1
  5. Day 5

    Buenos Aires

    A guided tour walks you through Buenos Aires' iconic neighborhoods this morning. You'll see the Italian-influenced La Boca with its colorful streets, the bohemian Palermo district full of eateries and galleries, and La Recoleta Cemetery where Eva Perón is buried. For dinner, you have three restaurants to choose from.

    Accommodation
    Hotel (Buenos Aires)

    Included Activities

    • Guided discovery of La Boca neighborhood
    • Guided exploration of Palermo neighborhood
    • Visit to La Recoleta Cemetery

    Optional Activities

    • Dinner at Fogon Asado - South American barbecued meats
    • Dinner at Fervor - Old-world steakhouse with Argentine cuisine featuring grilled meats and seafood
    • Dinner and Tango Show - Argentine dishes accompanied by a passionate tango show
    Landmarks
    La Boca
    Palermo
    La Recoleta Cemetery
  6. Day 6

    Buenos Aires

    You get to pick how you spend your day with three options. Either cruise through the rivers and canals of the Paraná Delta in the island town of Tigre, visit Plaza San Martin and other landmarks to explore Buenos Aires' Parisian side, or tour the iconic Teatro Colón opera house.

    Accommodation
    Hotel (Buenos Aires)

    Optional Activities

    • Tigre Cruise - Cruise over the rivers and canals of the Paraná Delta
    • Parisian Walking Tour - Discover the Parisian character of Buenos Aires, visiting Plaza San Martin and Plazoleta Pellegrini
    • Teatro Colón Tour - Tour of the iconic Teatro Colón opera house, noted for its impeccable acoustics
    Landmarks
    Tigre
    Paraná Delta
    Plaza San Martin
    Teatro Colón
  7. Day 7

    Buenos Aires to Iguazú Falls

    Flying to Iguazu Falls today, you'll arrive on the Argentine side where the falls straddle the border with Brazil. You'll board the Rainforest Ecological Train to reach walkways and viewing points, including one overlooking the 80-metre-deep Devil's Throat. Your hotel, Gran Melia Iguazu, is the only one actually inside the national park.

    Accommodation
    Hotel (Iguazú Falls)

    Included Activities

    • Rainforest Ecological Train experience
    • Viewing points including Devil's Throat
    Landmarks
    Iguazú Falls
    Devil's Throat
    Iguazú National Park
    Itinerary Image 1
  8. Day 8

    Iguazú Falls

    You'll spend the day taking in views of Iguazu Falls from the Brazilian side with leisurely walks between viewing platforms. Later, pick your own adventure either a jet boat safari to get close to the cascades or a helicopter ride for aerial views. The evening wraps up with a sommelier-led wine tasting and cheese pairings at your hotel.

    Meals
    Dinner (Wine tasting with cheese pairings)
    Accommodation
    Hotel (Iguazú Falls)

    Included Activities

    • Leisurely walks on Brazilian side viewing platforms
    • Wine tasting and cheese pairings at Gran Melia Iguazú

    Optional Activities

    • Jet Boat Safari - Close-up experience of Iguazú Falls' roaring cascades
    • Helicopter Ride - Scenic aerial views of Iguazú Falls
    Landmarks
    Iguazú Falls
  9. Day 9

    Iguazú Falls to Rio de Janeiro

    You have some free time to explore at leisure this morning before flying to Rio de Janeiro. After transferring to your art deco hotel across from Copacabana Beach, you'll have dinner at the hotel and can take in views of the golden sand and ocean.

    Meals
    Dinner (Dinner at hotel)
    Accommodation
    Hotel (Copacabana Palace)
    Landmarks
    Copacabana Beach
    Itinerary Image 1
  10. Day 10

    Rio de Janeiro

    Starting early, you'll head up to Corcovado mountain to see the Christ the Redeemer statue, an art deco sculpture that dominates Rio's skyline with sweeping city views. Lunch features Brazilian barbecue at a local restaurant. By evening you're taking a cable car to Sugarloaf Mountain's summit to watch the sunset and toast the incredible views with a drink.

    Meals
    Lunch (Brazilian barbecue at local restaurant)
    Accommodation
    Hotel (Copacabana Palace)

    Included Activities

    • Visit to Corcovado and Christ the Redeemer statue with panoramic views
    • Lunch at local restaurant with Brazilian barbecue
    • Cable car to Sugarloaf Mountain summit for sunset and drinks
    Landmarks
    Corcovado
    Christ the Redeemer
    Sugarloaf Mountain
  11. Day 11

    Rio de Janeiro

    You have a Freedom of Choice activity today to see more of Rio. Either explore the Tijuca Rainforest by open-top jeep or take a boat tour along Guanabara Bay to see Rio's beautiful coastline from the water.

    Accommodation
    Hotel (Copacabana Palace)

    Optional Activities

    • Jeep Tour - Discover the beauty of the Tijuca Rainforest by open-top jeep
    • Guanabara Bay Boat Tour - Half-day boat tour of Rio de Janeiro's beautiful coastline through tranquil waters
    Landmarks
    Tijuca Rainforest
    Guanabara Bay
  12. Day 12

    Rio de Janeiro to Lima

    Early this morning you're transferring to the airport for your flight to Lima. Your guide meets you and you'll have lunch at Café del Museo before visiting the Larco Museum. Later you'll head to your hotel to settle in.

    Meals
    Lunch (Lunch at Café del Museo)
    Accommodation
    Hotel (Country Club Lima Hotel), Hotel (InterContinental Real Lima Miraflores)

    Included Activities

    • Lunch at Café del Museo
    • Visit to Larco Museum
    Landmarks
    Larco Museum
    Itinerary Image 1
  13. Day 13

    Lima

    You're exploring Lima's World Heritage historic centre with a guide today. After that, you'll travel to a private hacienda for a signature experience with traditional South American cuisine and a Peruvian Paso horse show. The day ends with a visit to the ruins of Pachacamac.

    Meals
    Lunch (Traditional South American fare at private hacienda)
    Accommodation
    Hotel (Country Club Lima Hotel), Hotel (InterContinental Real Lima Miraflores)

    Included Activities

    • Guided discovery of Lima's World Heritage-listed historic centre
    • Lunch at private hacienda with traditional South American fare
    • Peruvian Paso horse show
    • Visit to ruins of Pachacamac
    Landmarks
    Lima Historic Centre
    Pachacamac
  14. Day 14

    Lima to Sacred Valley

    After breakfast you're flying to Cusco, the ancient Inca capital. From there you head to the Sacred Valley where you'll have a signature experience at a working corn farm. You'll enjoy farm-to-table lunch and learn about local cuisine traditions before arriving at your hotel.

    Meals
    Lunch (Farm-to-table lunch at working corn farm)
    Accommodation
    Hotel (Explora Sacred Valley)

    Included Activities

    • Flight to Cusco
    • Visit to working corn farm at Hacienda Sarapampa
    • Farm-to-table lunch at Hacienda Sarapampa
    Landmarks
    Cusco
    Sacred Valley
    Itinerary Image 1
  15. Day 15

    Sacred Valley

    You're visiting a small community in the Sacred Valley where locals will welcome you. Watch a traditional weaving demonstration to see how Peru's colorful textiles are made by hand, then enjoy traditional lunch with views of the Andes. After that, you'll explore the glistening Salt Mines of Maras and the fascinating circular terraces at Moray before having dinner at your hotel.

    Meals
    Lunch (Traditional lunch with Andes mountains and surrounding valleys views), Dinner (Dinner at hotel)
    Accommodation
    Hotel (Explora Sacred Valley)

    Included Activities

    • Welcome by local Misminay community
    • Traditional weaving demonstration
    • Traditional lunch with Andes views
    • Visit to Salt Mines of Maras
    • Visit to Moray archaeological site with Incan circular terraces
    • Guided exploration of Sacred Valley
    Landmarks
    Misminay Community
    Salt Mines of Maras
    Moray
    Andes Mountains
    Itinerary Image 1
  16. Day 16

    Sacred Valley to Aguas Calientes

    You're boarding Inca Rail's First Class train today for a journey through forested landscapes to Aguas Calientes, the gateway to Machu Picchu. You'll have a gourmet Andean-inspired lunch on board while taking in the views. After arriving, you have free time before dinner at your hotel.

    Meals
    Lunch (Gourmet Andean-inspired lunch on Inca Rail First Class train), Dinner (Dinner at hotel)
    Accommodation
    Hotel (Sumaq Machu Picchu Hotel)

    Included Activities

    • Inca Rail First Class Machu Picchu Train
    • Gourmet Andean-inspired lunch on board train
    Landmarks
    Aguas Calientes
    Itinerary Image 1
  17. Day 17

    Aguas Calientes to Cusco

    This morning a local guide takes you through Machu Picchu, the Lost City of the Incas. You'll spend time exploring this heritage site and natural setting. Later you board the PeruRail Vistadome train for the return trip to Sacred Valley, then transfer by coach to Cusco for the evening at your hotel in the historic city center.

    Accommodation
    Hotel (Cusco)

    Included Activities

    • Locally guided exploration of Machu Picchu
    • PeruRail Vistadome Machu Picchu Train return journey
    Landmarks
    Machu Picchu
  18. Day 18

    Cusco

    A guided tour takes you through Cusco starting at Plaza de Armas in the historic centre. This afternoon you choose your own activity either a cooking class to learn traditional Peruvian dishes or visit the 15th-century dry stone Sacsayhuamán citadel. Tonight you're having dinner at MAP Café in the courtyard of the Museum of Pre-Columbian Art.

    Meals
    Dinner (Dinner at MAP Café in the central courtyard of the Museum of Pre-Columbian Art)
    Accommodation
    Hotel (Cusco)

    Included Activities

    • Guided discovery of Cusco
    • Visit to Plaza de Armas

    Optional Activities

    • Peruvian Cooking Class - Learn to prepare traditional Peruvian dishes and discover traditional ingredients
    • Sacsayhuamán Citadel Visit - Explore the 15th-century dry stone archaeological site
    Landmarks
    Plaza de Armas
    Sacsayhuamán
    Museum of Pre-Columbian Art
  19. Day 19

    Cusco to Amazon (Iquitos)

    You're boarding an early flight to Iquitos in the Peruvian Amazon. Your coach takes you through the rainforest region with commentary and a boxed lunch along the way. At Nauta you board the boutique Delfin III vessel. After meeting your naturalist guides and settling into your cabin, you'll take a skiff exploration along the Marañón River as dusk falls, looking for wildlife. Dinner is a three-course meal back on board.

    Meals
    Lunch (Boxed lunch en route to Nauta), Dinner (Three-course dinner on board Delfin III)
    Accommodation
    Hotel (Amazon River)

    Included Activities

    • Coach transfer through rainforest with commentary
    • Skiff exploration along Marañón River at dusk
    • Three-course dinner on board Delfin III
    Landmarks
    Iquitos
    Peruvian Amazon
    Marañón River
    Itinerary Image 1
  20. Day 20

    Amazon River Cruise

    This morning you're meeting a local Shaman to learn about rainforest plant uses for medicine and what it takes to become a Shaman. After lunch on board, you'll take to the water by kayak, paddling along quieter tributaries. Keep watch for birds, monkeys, and maybe the elusive pink river dolphin as small communities pass by on the riverbanks.

    Meals
    Lunch (Lunch on board Delfin III)
    Accommodation
    Hotel (Amazon River)

    Included Activities

    • Meeting with local Shaman to learn about rainforest plants and medicine
    • Kayaking along tributary tributaries
    Landmarks
    Peruvian Amazon
  21. Day 21

    Amazon River Cruise

    You're heading out in a skiff with your naturalist guide for fishing and wildlife spotting in Nauta Caño, where piranha live in the river. You'll visit a local community to see how residents use forest species for food and household items. In the afternoon, a trail walk takes you through the rainforest to see the ecosystem up close with frogs, snakes, and insects. You'll also reach the confluence where the Marañón and Ucayali rivers merge, considered the point where the Amazon River begins.

    Meals
    Lunch (Lunch on board Delfin III)
    Accommodation
    Hotel (Amazon River)

    Included Activities

    • Skiff exploration in Nauta Caño with fishing opportunity
    • Visit to local community
    • Rainforest trail walk at Nauta Caño
    • Visit to confluence of Marañón and Ucayali rivers
    Landmarks
    Nauta Caño
    Marañón River
    Ucayali River
  22. Day 22

    Amazon to Iquitos

    This morning you're leaving the Delfin III. On the way to Iquitos airport, you'll stop at the Tropical Amazon Aquarium to see more than 60 species of tropical fish and learn about the river's aquatic biodiversity. Your South American adventure wraps up at Iquitos Airport.

    Included Activities

    • Visit to Tropical Amazon Aquarium
    Landmarks
    Tropical Amazon Aquarium
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Tour ID: 307089

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    Chile
    S/.
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    Peru
  • Plugs & Adapters

    As a traveler from New Zealand you will need an adaptor for type L.

    Type I
    Argentina
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  • Vaccines
    • These are only indications, so please visit your doctor before you travel to be 100% sure.
    • Typhoid - Recommended for Argentina.Brazil.Chile.Peru. Ideally 2 weeks before travel.
    • Hepatitis A - Recommended for Argentina.Brazil.Chile.Peru. Ideally 2 weeks before travel.
    • Hepatitis B - Recommended for Argentina.Brazil.Chile.Peru. Ideally 2 months before travel.
    • Rabies - Recommended for Argentina.Chile.Peru. Ideally 1 month before travel.
    • Yellow fever - Recommended for Argentina.Brazil.Peru. Ideally 10 days before travel.
    • Tuberculosis - Recommended for Brazil.Peru. Ideally 3 months before travel.
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    • Here is an indication for which countries you might need a visa. Please contact the local embassy for help applying for visas to these places.
  • Payment information
    • For any tour departing before April 5th, 2026 a full payment is necessary. For tours departing after April 5th, 2026, a minimum payment of $1,100 is required to confirm your booking with APT. The final payment will be automatically charged to your credit card on the designated due date. The final payment of the remaining balance is required at least 120 days prior to the departure date of your tour. TourRadar never charges you a booking fee and will charge you in the stated currency.
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