4-Week South America Tour Packages
4.5 stars on(8,166 reviews)- Choose from 50+ South America tours
- 150+ verified reviews from TourRadar travelers
- 24/7 customer support
Insider tips: Recommended 4-week South America itineraries
Compiled by

NinaSouth America travel expert at TourRadar
28 Day Antarctica Itinerary, incl. Weddell Sea and South Georgia Island
A grand 28-day polar expedition through South America takes you to Ushuaia, South Georgia Island, and the Antarctic Peninsula. The voyage includes 9 full days among the Weddell Sea's ice shelves, with visits to Brown Bluff and Kinnes Cove. Expert-led excursions offer prime wildlife viewing opportunities.
- Days 1-3
Ushuaia and Drake Passage
- Days 4-6
Journey to South Georgia
- Days 7-8
Sea Days
- Day 9
South Sandwich Islands
- Days 10-12
Heading South
- Days 13-14
New Swabia
- Days 15-23
Deep Weddell Sea
Explore the Filchner, Ronne and Larsen ice shelves. Look for Weddell seals breeding in these remote waters. The incredibly clear water offers visibility up to 150 feet. The ship moves carefully through dense ice fields.
- Day 24
Brown Bluff & Kinnes Cove
Stop at Brown Bluff's volcanic cliffs if possible. Watch Adelie penguin colonies and keep your camera ready for nearby whales.
- Day 25
Elephant Island
Visit Point Wild, where Shackleton's crew waited for rescue. While landing is uncommon due to weather, Zodiac rides offer good views of this historic location.
- Days 26-27
Drake Passage Return
Head back through typically calmer Drake Passage waters. Sort photos and attend final lectures.
- Day 28
Ushuaia
Return to Ushuaia early morning. Book afternoon flights to allow for weather delays.
26 Day South America Itinerary, incl. Lima and Buenos Aires
Iconic South American sites unfold over 26 days, visiting 14 cities from Lima to Buenos Aires. The journey includes Sacred Valley trekking to Machu Picchu, Lake Titicaca's floating islands, and Salar de Uyuni salt flats. Accommodations vary from Amazon jungle lodges to city hotels, with local expert guides.
- Days 1-3
Peru's Coast & Amazon
Begin in Lima and explore the Miraflores district, known for its ocean views at Parque del Amor. On Day 2, fly to Puerto Maldonado for your Amazon adventure. You'll take a motorized canoe to your jungle lodge after storing your main luggage in town. Spend two days looking for wildlife on jungle walks and night boat rides to spot caimans. Pack light, quick-dry clothes and strong insect repellent. The humidity is high and mosquitoes are active.
- Days 4-10
Sacred Valley & Machu Picchu Circuit
Fly to Cusco at 11,152 feet. Take your first day slow to adjust to the altitude. Visit Plaza de Armas and San Pedro Market in the historic center. Next, visit the Sacred Valley's local communities and markets. Choose your path to Machu Picchu: Classic Inca Trail (4 days): A challenging trek reaching 13,828 feet at Dead Woman's Pass, with tent camping; Quarry Trail: A less busy route with ruins to explore; Train Option: A scenic rail journey to Aguas Calientes. A recent hiker shared: "The altitude was tough but seeing the sunrise over Machu Picchu through the Sun Gate made every step worth it. Pack hiking poles - your knees will thank you on the descent."
- Days 11-13
Lake Titicaca
- Days 14-16
La Paz & Salt Flats
Enter Bolivia and visit La Paz at 11,942 feet. Check out the Witches' Market and historic streets. Take an overnight bus to Uyuni for the salt flats. Spend a day taking photos of the white landscape and islands covered in cacti. Bring good sunglasses and sunscreen. The salt flats are extremely bright.
- Days 17-21
Atacama & Northern Argentina
- Days 22-26
Buenos Aires
25 Day South America Itinerary, incl. La Paz and Rio de Janeiro
Rich landscapes unfold over 25 days across 11 destinations from La Paz to Rio. The route encompasses Bolivia's salt flats, Chile's Atacama Desert, Argentina's colonial cities, and Brazil's tropical islands. Guided tours of Iguazu Falls from both countries and traditional estancia stays included.
- Days 1-2
La Paz, Bolivia
Welcome to the world's highest capital city at 3,500m. The fascinating Witches' Market (Mercado de Hechiceria) is a must-see, where local shamans sell traditional remedies and ceremonial items. Pack lots of warm layers since La Paz gets quite cold at night. Take an overnight bus to Uyuni - you'll get blankets and reclining seats for the journey.
- Days 3-5
Salar de Uyuni & Atacama Desert
The otherworldly Salar de Uyuni salt flats start with a visit to the Train Cemetery. Next up is Chile's Atacama Desert, where you'll find the red waters of Laguna Colorada full of flamingos. Expect basic facilities and very cold desert nights. One traveler shared: "The salt flats at sunrise were incredible, but bring warm socks and layers - I wasn't prepared for how cold it would be at dawn."
- Days 6-8
San Pedro de Atacama & Salta
Take time to explore San Pedro's old town square and try an astronomy tour under the clear desert sky. The drive to Salta, Argentina is long but beautiful. They call it "La Linda" (the beautiful) for good reason. You can climb 1,070 steps up Cerro San Bernardo or take the cable car for amazing valley views.
- Days 9-13
Buenos Aires & Uruguay
A quick flight takes you to energetic Buenos Aires. Walk through colorful La Boca and the historic San Telmo market. Take a boat to Uruguay's Colonia del Sacramento, a UNESCO site. Visit Montevideo before staying at a traditional estancia (ranch) for a real gaucho experience. A past guest wrote: "The estancia stay was a highlight - learning to ride horses and sharing meals with the local family gave us real insight into Uruguayan culture."
- Days 14-17
Iguazu Falls
- Days 18-20
Paraty & Ilha Grande
- Days 21-25
Rio de Janeiro
What people love about 4-week South America tours
- Ultimate South America (Train To Machu Picchu)
The continued Peru experience was one of the most memorable place for its food, culture, and for the curated itinerary that kept us busy and exploring!
More about South America
10 Best South America Backpacking Tours & Trips 2025/202610 Best Adventure Trips for Couples 2025/202610 Best South America Honeymoon Packages & Tours 2025/202610 Best South America Travel Specialists (with Reviews)Weather in South America in 2025/2026What is the best time to visit South America in 2025/2026?