2-Week Panama Tour Packages

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Insider tips: Recommended 2-week Panama itineraries

Compiled by

SteffPanama travel expert at TourRadar

14 Days in Panama, incl. Panama City and Bocas del Toro
Solo travelers will appreciate Panama's diversity at approx. $270/day. The itinerary includes crossing the Panama Canal, touring UNESCO-listed Casco Antiguo, and immersing in local culture at Oria Arriba village. Accommodations include the welcoming Best Western Plus Panama Zen.
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- Days 1-3
  Panama City
  Start your Panama adventure in this modern, cosmopolitan city. Plan to land at Tocumen International Airport in the afternoon to skip the rush hour traffic. Take a 4-hour boat trip through the Panama Canal on day 2. Get to the dock by 7:30 AM for the best chances of seeing wildlife along the banks. Spend day 3 in the UNESCO-listed Casco Antiguo district. You'll want comfortable shoes for the cobblestone streets and plenty of water since the humidity can be intense.
- Day 4
  El Valle de Antón
  Drive 2.5 hours to the world's largest inhabited volcanic crater. Visit the local market before 9 AM to see the freshest produce. Pack good shoes for the El Macho waterfall trail as it gets slippery after rain. Plan to visit the mineral springs in late afternoon when it's cooler.
- Days 5-6
  Las Tablas & Rural Panama
  Discover authentic Panamanian culture in the Azuero Peninsula. Look for the intricate polleras (traditional dresses) in Parita. Each one takes months to make and can cost up to $3,000. When you visit Oria Arriba village, bring small bills to buy local crafts. The money helps support their community school. If you swim at the Pacific beaches near Playa Venao, stay in the marked swimming areas due to strong currents.
- Days 7-8
  Boquete
  The 4.5-hour drive to this mountain town takes you up to 1,200 meters where you'll notice cooler temperatures. Walk the suspension bridges early before clouds move in. If you're interested in coffee plantation tours, book ahead during harvest season from December to March.
- Days 9-11
  Bocas del Toro
  Take a morning boat from Almirante to get the most out of your time in these Caribbean islands. The 30-minute crossing can get rough so sit in the middle of the boat for more stability. Remember water shoes for the rocky parts of the hike to Red Frog Beach. Go snorkeling at Coral Cay in the morning when the water is clearest before afternoon winds pick up.
- Days 12-14
  Return to Panama City & Departure
  Book your Bocas to Panama City flight for the afternoon since morning fog often causes delays. Use your last full day to visit the Amador Causeway. It offers the best views of the city skyline, especially at sunset.
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12 Day Panama Itinerary, incl. Panama City and Bocas del Toro
The 12-day Panamanian adventure showcases Panama City's Miraflores Locks, Bocas del Toro's marine paradise, Boquete's cloud forests, and Santa Catalina's UNESCO-listed Coiba Island. Guests enjoy 11 breakfasts, 7 lunches, and 4-star accommodations throughout.
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- Days 1-3
  Panama City Region:
  Start in Panama City. Spend your first evening in Costa del Este, an upscale area good for orientation. Stay in the Financial District for security and convenience. Visit Casco Viejo early on day 2 before the streets heat up. Check online schedules to time your Miraflores Locks visit with ship transits. On day 3, be ready for a 6:30 AM check-in at Flamenco Marina for your canal cruise. Bring extra snacks even though meals are included. The 6-hour journey can feel long.
- Days 4-6
  Bocas del Toro:
  Fly to Bocas del Toro (1 hour). Weather here is unpredictable so have backup plans ready. Visit Dolphin Bay in early morning when the water is calm. Use reef-safe sunscreen at Coral Cay to protect marine life. Boat trips to Ngobe communities take 30 minutes. If you get seasick easily bring medicine. The drive to Boquete takes 3.5 hours. Sit up front if you don't like winding roads.
- Days 7-8
  Boquete Region:
  The Cloud Forest zip-line stretches 3 km across 12 cables. You'll need closed-toe shoes and a light jacket for the cooler elevation. Visit coffee plantations between December and March during harvest season. The drive to Santa Catalina takes 4 hours on mountain roads. Download your maps since cell service is limited.
- Days 9-10
  Santa Catalina:
  Coiba National Park offers whale watching from June to October but expect rougher seas. Know your swimming ability before booking water activities. The currents are strong here. If you're an experienced surfer use your free day to catch some of Panama's best waves.
- Days 11-12
  Return to Panama City:
  Leave early for the 5.5-hour drive back to Panama City to beat traffic. Give yourself 3 hours at Tocumen International Airport. Security lines can get long in peak season.
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13 Days in Panama, incl. Panama City and Bocas del Toro
A 13-day adventure winds through 6 unique destinations, from Panama City's modern skyline to Bocas del Toro's Caribbean charm. Visit Boquete's cloud forests, El Valle's volcanic crater, historic Natá de los Caballeros, and traditional villages like Oria Arriba.
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- Days 1-3
  Panama City
  Start in the capital with a morning arrival to dodge peak traffic from Tocumen Airport (45-60 minutes to city center). Take two full days to explore the city. Visit Miraflores Locks around 9 AM to catch the first ships passing through the Panama Canal. Walk through historic Casco Antiguo in early morning or late afternoon when the heat is less intense.
- Day 4
  El Valle de Antón
  Take a 2.5-hour drive from Panama City to this town set in the world's largest inhabited volcanic crater. The 600m elevation offers a nice break from coastal heat. Visit the butterfly sanctuary in the morning when butterflies are most active. Bring good walking shoes for the El Macho waterfall trail. The path gets slippery after rain.
- Days 5-6
  Las Tablas Region
  This cultural hub is about 3 hours from El Valle. Check out the historic Natá de los Caballeros church and watch traditional mask-making in Parita village. Head to Playa Venao in late afternoon for better temperatures and good surfing conditions.
- Days 7-8
  Boquete
  Plan for a 5-hour drive to this mountain town. Pack layers for the 1,200m elevation. Morning temperatures can be cool. Take the hanging bridges trail before 10 AM for the best cloud forest views. Coffee farm tours work well in the afternoon when processing is in full swing.
- Days 9-11
  Bocas del Toro
  Take a morning shuttle to Almirante (3 hours) and a 30-minute water taxi to Isla Colón. Sit in the middle of the boat if you want a smoother ride. Pack water shoes for Red Frog Beach's muddy paths. Go snorkeling at Coral Cay in the morning when waters are calm.
- Days 12-13
  Panama City
  Fly back to Panama City (1 hour). Book your final departure flight in the afternoon to allow time for potential weather delays from Bocas.
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