2-Week Panama Tour Packages

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Insider tips: Recommended 2-week Panama tour itineraries

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SteffPanama travel expert at TourRadar

12 Day Panama Itinerary, incl. Panama City and Bocas del Toro
The 12-day Panamanian adventure showcases Panama City's Miraflores Locks, Bocas del Toro's marine paradise, Boquete's cloud forests, and Santa Catalina's UNESCO-listed Coiba Island. Guests enjoy 11 breakfasts, 7 lunches, and 4-star accommodations throughout.
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- Days 1-3
  Panama City Region:
  Start in Panama City. Spend your first evening in Costa del Este, an upscale area good for orientation. Stay in the Financial District for security and convenience. Visit Casco Viejo early on day 2 before the streets heat up. Check online schedules to time your Miraflores Locks visit with ship transits. On day 3, be ready for a 6:30 AM check-in at Flamenco Marina for your canal cruise. Bring extra snacks even though meals are included. The 6-hour journey can feel long.
- Days 4-6
  Bocas del Toro:
  Fly to Bocas del Toro (1 hour). Weather here is unpredictable so have backup plans ready. Visit Dolphin Bay in early morning when the water is calm. Use reef-safe sunscreen at Coral Cay to protect marine life. Boat trips to Ngobe communities take 30 minutes. If you get seasick easily bring medicine. The drive to Boquete takes 3.5 hours. Sit up front if you don't like winding roads.
- Days 7-8
  Boquete Region:
  The Cloud Forest zip-line stretches 3 km across 12 cables. You'll need closed-toe shoes and a light jacket for the cooler elevation. Visit coffee plantations between December and March during harvest season. The drive to Santa Catalina takes 4 hours on mountain roads. Download your maps since cell service is limited.
- Days 9-10
  Santa Catalina:
  Coiba National Park offers whale watching from June to October but expect rougher seas. Know your swimming ability before booking water activities. The currents are strong here. If you're an experienced surfer use your free day to catch some of Panama's best waves.
- Days 11-12
  Return to Panama City:
  Leave early for the 5.5-hour drive back to Panama City to beat traffic. Give yourself 3 hours at Tocumen International Airport. Security lines can get long in peak season.
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13 Days in Panama, incl. Panama City and Bocas del Toro
A 13-day adventure winds through 6 unique destinations, from Panama City's modern skyline to Bocas del Toro's Caribbean charm. Visit Boquete's cloud forests, El Valle's volcanic crater, historic Natá de los Caballeros, and traditional villages like Oria Arriba.
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- Days 1-3
  Panama City
  Start in the capital with a morning arrival to dodge peak traffic from Tocumen Airport (45-60 minutes to city center). Take two full days to explore the city. Visit Miraflores Locks around 9 AM to catch the first ships passing through the Panama Canal. Walk through historic Casco Antiguo in early morning or late afternoon when the heat is less intense.
- Day 4
  El Valle de Antón
  Take a 2.5-hour drive from Panama City to this town set in the world's largest inhabited volcanic crater. The 600m elevation offers a nice break from coastal heat. Visit the butterfly sanctuary in the morning when butterflies are most active. Bring good walking shoes for the El Macho waterfall trail. The path gets slippery after rain.
- Days 5-6
  Las Tablas Region
  This cultural hub is about 3 hours from El Valle. Check out the historic Natá de los Caballeros church and watch traditional mask-making in Parita village. Head to Playa Venao in late afternoon for better temperatures and good surfing conditions.
- Days 7-8
  Boquete
  Plan for a 5-hour drive to this mountain town. Pack layers for the 1,200m elevation. Morning temperatures can be cool. Take the hanging bridges trail before 10 AM for the best cloud forest views. Coffee farm tours work well in the afternoon when processing is in full swing.
- Days 9-11
  Bocas del Toro
  Take a morning shuttle to Almirante (3 hours) and a 30-minute water taxi to Isla Colón. Sit in the middle of the boat if you want a smoother ride. Pack water shoes for Red Frog Beach's muddy paths. Go snorkeling at Coral Cay in the morning when waters are calm.
- Days 12-13
  Panama City
  Fly back to Panama City (1 hour). Book your final departure flight in the afternoon to allow time for potential weather delays from Bocas.
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13 Day Panama Itinerary, incl. Panama City and Bocas del Toro
The 13-day tour spans 5 Panamanian cities: Panama City's colonial quarter, El Valle's volcanic crater, Las Tablas' cultural heritage, Boquete's cloud forests, and Bocas del Toro's Caribbean islands. Highlights include partial Panama Canal crossing and visits to Oreba Chocolate Farm.
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- Days 1-3
  Panama City
  Begin your journey in Panama's capital, where modern architecture meets colonial history. Take a morning Panama Canal cruise from Panama City to Gamboa (4 hours) to watch ships pass through the Miraflores Locks. Get to the Miraflores Visitor Center by 8:30 AM to beat the crowds. Explore Panama Viejo's 16th-century ruins before visiting the historic Casco Antiguo district. Visit the Causeway at sunset for perfect skyline photos.
- Day 4
  El Valle de Anton
  Take a 2.5-hour drive west on the Panamericana to this town nestled in the world's largest inhabited volcanic crater. The weather is cooler here than the coast. Visit El Macho waterfall in the morning to avoid afternoon rain. Wear sturdy shoes as the trails get slippery. Stop by the ancient petroglyphs at La Piedra Pintada.
- Days 5-6
  Las Tablas Region
  Experience authentic Panama in the countryside. Visit the historic 1520 church in Natá de los Caballeros. Watch traditional sugar cane processing in Oria Arriba, and tobacco farming if in season. Wear light clothes for the inland heat. The Pacific beaches make great afternoon stops.
- Days 7-8
  Boquete
  This mountain town at 1,200m enjoys mild weather all year. Walk the cloud forest suspension bridges early when visibility is best. Take a coffee plantation tour, especially during harvest season (December-March). Bring something warm for cool evenings.
- Days 9-11
  Bocas del Toro
  Drive to Almirante (3-4 hours), stopping at Oreba Chocolate Farm. Take a boat to Colón Island. Go snorkeling at Coral Cay in the morning when the water is calm. Visit Red Frog Beach on Bastimentos Island by water taxi. Book morning trips as afternoon storms can affect boat schedules. A visitor shared: "The beach got its name from the tiny red frogs you can spot in the jungle behind the sand – they're smaller than your thumbnail but brilliantly colored."
- Days 12-13
  Return to Panama City
  Fly back to the capital. Consider adding time to visit the San Blas Islands but book accommodations early.
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