Mekong Cruises from Ho Chi Minh City
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10 best Mekong river cruises from Ho Chi Minh City
Compiled by

MelissaHo Chi Minh City travel expert at TourRadar
- From the Mekong Delta to the Angkor Temples (port-to-port cruise) (from Ho Chi Minh City to Siem Reap)
- Majestic Mekong Cruise Ho Chi Minh City → Siem Reap (2025)
- Essential Vietnam and Cambodia Ho Chi Minh City to Siem Reap (2025)
- 8-Day Majestic Mekong Cruise 2025-2026|2026-2027 - 8 Days (from Ho Chi Minh City to Phnom Penh)
- 7-Night Christmas Cruise on the Mekong Navigator: Vietnam & Cambodia
- Majestic Mekong Cruise Ho Chi Minh City → Siem Reap (2027)
- Vietnam and Cambodia Highlights Ho Chi Minh City → Siem Reap (2027)
- From the Mekong Delta to Siem Reap
- From the Mekong Delta to Siem Reap (port-to-port cruise) (12 destinations)
- The Mekong in a different way - Between adventure and must-seesites (port-to-port cruise) (from Ho Chi Minh City to Siem Reap)
From the Mekong Delta to the Angkor Temples (port-to-port cruise) (from Ho Chi Minh City to Siem Reap)
2 Reviews by TourRadar travelers“Knowledgeable, fluent in English, friendly, and concerned about our safety always.”
Awadesh, traveled in October
From Liberty Central Riverside Hotel in Ho Chi Minh City, this 11-day Mekong cruise spans Cu Chi tunnels and Cho Gao canal. The route winds through Vietnam's Vinh Long and Sa Dec before reaching Cambodia's Phnom Penh, culminating at Siem Reap's Angkor temples.
Duration 11 days Destinations Ho Chi Minh City, My Tho, Vinh Long, Cai Be, Sa Dec, Chau Doc, Phnom Penh, Koh Chen, Kampong Tralach, Kampong ChhnangSee all destinations Age Range up to 99 year olds Ships RV IndochineRV Indochine II RV Lan Diep River Mekong Operator CroisiEurope River Cruises From $6,684
41% Off- NZ$3,971You save $2,713
A Mekong voyage from Ho Chi Minh City passes through My Tho port to Cambodian highlights including Phnom Penh and Angkor Ban. Traditional riverside villages and historic sites lead to the final destination of Siem Reap.
Duration 8 days Destinations Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Tan Chau, Mekong Delta, Phnom Penh, Oudong, Koh Chen, Angkor BanSee all destinations Age Range up to 99 year olds River Mekong Operator Travel Marvel From
41% Off- NZ$3,545+$650 upfront costs
After visiting Cu Chi Tunnels in Ho Chi Minh City, the RV Apsara navigates the Mekong through My Tho, Cai Be, and Sa Dec. The route enters Cambodia via Tan Chau, stops at Phnom Penh before reaching temple-rich Siem Reap.
Duration 12 days Destinations Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Tan Chau, Phnom Penh, Oudong, Koh Chen, Kampong Cham, Siem Reap Age Range up to 99 year olds River Mekong Operator APT From
41% Off- NZ$5,173
From Saigon Port, the route follows Cho Gao Canal to Ben Tre, Sa Dec and My An Hung villages. The ship heads north via Gieng Island and Tan Chau before entering Cambodia. Phnom Penh marks the end after visiting Oudong Monastery and Prek K'Dam.
Duration 8 days Destinations Ho Chi Minh City, Mekong Delta, Ben Tre, Sa Dec, My An Hung, Tan Chau, Oudong, Phnom Penh Age Range up to 90 year olds River Mekong Operator Emerald Cruises From $16,466
60% Off- NZ$6,585You save $9,881
Duration 8 days Destinations Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Tan Chau, Phnom Penh, Oudong, Koh Chen, Koh Oknha Tei, Angkor BanSee all destinations Age Range up to 99 year olds River Mekong Operator Travel Marvel From
60% Off- NZ$3,353
Duration 13 days Destinations Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Tan Chau, Phnom Penh, Oudong, Koh Chen, Angkor Ban, HancheySee all destinations Age Range up to 99 year olds River Mekong Operator APT From
60% Off- NZ$9,149
The voyage stretches 2,700 miles north from Liberty Central Riverside Hotel in Ho Chi Minh City, passing through My Tho and Chau Doc. The route winds through the narrow Chao Gao Canal, crosses into Cambodia through Phnom Penh, and concludes in Siem Reap. The colonial-styled RV Indochine II serves as your floating home during this 9-day expedition.
Duration 9 days Destinations Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Chau Doc, Phnom Penh, Koh Chen, Kampong Tralach, Tonle Sap Lake, Siem Reap Age Range up to 99 year olds Ships RV IndochineRV Indochine II RV Lan Diep River Mekong Operator CroisiEurope River Cruises From
60% Off- NZ$3,418
From the Mekong Delta to Siem Reap (port-to-port cruise) (12 destinations)
1 Review by TourRadar travelersDuration 9 days Destinations Ho Chi Minh City, My Tho, Vinh Long, Cai Be, Sa Dec, Chau Doc, Phnom Penh, Koh Chen, Kampong Tralach, Kompong ChhnangSee all destinations Age Range up to 99 year olds Ships RV IndochineRV Indochine II RV Lan Diep River Mekong Operator CroisiEurope River Cruises From
60% Off- NZ$3,874
The Mekong in a different way - Between adventure and must-seesites (port-to-port cruise) (from Ho Chi Minh City to Siem Reap)
2 Reviews by TourRadar travelersAn 11-day route starting with Ho Chi Minh City's Chinatown spans 10 cities across Vietnam and Cambodia. The ship passes through Chao Gao canal to My Tho, Sa Dec and Chau Doc, before entering Cambodia. Highlights include Phnom Penh's Royal Palace and Oudong before reaching Siem Reap.
Duration 11 days Destinations Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Chau Doc, Phnom Penh, Oudong, Kampong Tralach, Koh Chen, Siem Reap Age Range up to 99 year olds River Mekong Operator CroisiEurope River Cruises From
60% Off- NZ$4,467
What people love about Mekong Cruises from Ho Chi Minh City
- From the Mekong Delta to the Angkor Temples (port-to-port cruise) (from Ho Chi Minh City to Siem Reap)
Great experience will recommend
- 7-night Mekong Upstream Vietnam Cambodia on Mekong Navigator
You must book this tour!!!!
What our customers ask about Mekong Cruises from Ho Chi Minh City
What is the typical duration of Mekong River cruises starting from Ho Chi Minh City?
Mekong River cruises from Ho Chi Minh City typically span 8 to 15 days with 8-day journeys being the most common choice. The experience starts at Saigon Port where vessels like the Emerald Harmony begin their journey down the Saigon River toward Ben Tre in the Mekong Delta. Before boarding guests often stay at upscale accommodations such as the Sheraton Saigon Hotel and Towers blending urban exploration with river adventures. As one TourRadar traveler noted: "The perfect mix of relaxation and cultural immersion with each day bringing new discoveries along the river."
What are the main highlights to explore on the first day in Ho Chi Minh City?
Day one takes visitors through key sites including the Reunification Palace Notre Dame Cathedral Central Post Office and the vibrant Cholon district home to the Ba Thien Hau Pagoda. Tours start with lunch at hotels like Liberty Central Riverside or Sofitel Saigon Plaza. A TourRadar traveler mentioned: "The initial city tour gave us a great overview of Ho Chi Minh City's French colonial history and modern energy."
Where are the common embarkation points within Ho Chi Minh City?
Downtown Ho Chi Minh City serves as the starting point with pickup locations at prominent hotels like Le Meridien Saigon and Caravelle Hotel Saigon in District 1. Passengers then travel to My Tho Port roughly 70km away where vessels such as the Scenic Spirit and RV Apsara dock. According to TourRadar travelers: "The transfer from Ho Chi Minh City to My Tho port was smooth and well-organized making the start of our journey stress-free."
What's the best time of year to start a Mekong tour from Ho Chi Minh City?
October through January offers the most favorable conditions for Mekong tours with dry weather and mild temperatures. November December and January see the highest number of departures creating ideal conditions for exploring sites like the Tan My Floating community and Ben Tre's waterways. As one TourRadar traveler commented: "Traveling in December provided perfect weather conditions for both the city exploration and river cruise portions of our journey."
What unique cultural experiences are offered on Ho Chi Minh City Mekong tours?
The itineraries feature hands-on experiences at traditional candy workshops in Cai Be visits to floating markets rice paper making demonstrations and Apsara dance shows in Phnom Penh. Accommodations range from city stays at Liberty Central Riverside to river journeys aboard vessels like the RV Indochine II. According to a TourRadar traveler: "The local cultural activities and interactions with villagers along the Mekong were the highlight of our journey."
How long is the transfer from Ho Chi Minh City to the first cruise stop?
Travelers spend 2 hours traveling from Ho Chi Minh City to My Tho port followed by a 4-hour cruise to reach Cai Be the first overnight destination. Ships such as the Scenic Spirit and RV Apsara travel through the Cho Gao canal before anchoring. As one TourRadar traveler shared: "The transition from city to river life was fascinating watching the urban landscape gradually transform into the peaceful Mekong Delta."