10-Day South America Tour Packages
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Insider tips: Recommended 10-day South America tour itineraries
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NinaSouth America travel expert at TourRadar
10 Day South America Itinerary, incl. Buenos Aires and Rio de Janeiro
Five major cities reveal their secrets over 10 days. Stroll Buenos Aires' Avenida de Mayo, wander Colonia's historic quarter, immerse in ranch life near Tacuarembo, witness both sides of Iguazu Falls, and savor Rio's attractions from Copacabana to Christ the Redeemer. Includes 8 breakfasts and guided activities.

- Day 1
Buenos Aires, Argentina
Visit Buenos Aires' historic Microcentro district. Walk down Avenida de Mayo to see the Casa Rosada around 1 PM to avoid the morning business crowds. Head to San Telmo's cobblestone streets after 3 PM when the antique markets are fully operational. A recent visitor shared: "The afternoon wandering through San Telmo's markets was perfect timing – fewer tourists and better bargaining opportunities."

- Day 2
Colonia del Sacramento, Uruguay
- Days 3-5
Uruguayan Estancia Stay
Get ready for a long travel day: 3 hours to Montevideo followed by 5 hours to Tacuarembo. Pack snacks since the bus doesn't make stops. The ranch experience includes optional early morning farm work with the gauchos. A previous guest noted: "Watching the gauchos work with the cattle at sunrise was incredible – but be prepared for basic accommodations and sometimes brown water."

- Days 6-8
Iguazu Falls
Take the overnight bus to Puerto Iguazu (12 hours). Visit both sides of the falls: Brazilian side offers panoramic views (2-3 hours needed) while the Argentine side gets you closer to the action (full day). Arrive at the Argentine side before 9 AM to avoid crowds. Bring rain gear and shoes with good grip. The boat ride to the falls' base is worth it but pack spare clothes.

- Days 9-10
Rio de Janeiro
Fly to Rio in the morning. Visit Copacabana Beach in late afternoon when it's cooler and more locals are out. Plan your Christ the Redeemer visit after 11 AM when morning fog typically clears. Use official taxis or rideshare apps for safety. On your last day you might want to start early with Sugarloaf Mountain to beat the crowds.

10 Days in Argentina & Bolivia, incl. Salta and La Paz
The flavors and landscapes of 6 distinct cities unfold over 10 days. Taste Salta's wine country, marvel at San Pedro's Moon Valley, and cross Uyuni's salt flats. Highlights include Cafayate vineyards and La Paz's cable car rides. Includes 9 nights accommodation and most meals.

- Day 1
Salta, Argentina
- Day 2
Cafayate Wine Region
Take a full-day trip to Cafayate through the Lerma Valley (3 hours each way). The morning drive through Quebrada de las Conchas offers stunning rock formations. Stop at the Devil's Throat viewpoint for photos. Visit the Torrontés wineries in the afternoon when they're less busy. Pack a light jacket for the valley's cool temperatures.

- Day 3
Salta to San Pedro de Atacama
- Day 4
San Pedro de Atacama
- Day 5
Atacama to Uyuni
- Day 6
Bolivian Desert
- Day 7
Uyuni Salt Flats
- Day 8
La Paz
- Day 9
La Paz Exploration
- Day 10
Departure from La Paz
10 Days in South America, incl. Atacama Desert and Uyuni Salt Flats
10-day South American adventure covering 3 countries and iconic sites like Uyuni Salt Flats and Valle de la Luna. Journey through high-altitude lagoons, spot flamingos at Laguna Colorada, and explore colonial Salta. Stay at Campo Base Hostel and salt refuges while discovering remote Andean landscapes.

- Days 1-2
Salta, Argentina
Your journey starts in historic Salta. Visit the High Mountain Museum when you arrive to get familiar with the region's geography. On your second day choose between trips to Quebrada de Cafayate or Humahuaca. Book wine tours for the morning when it's cooler. Get some rest at your hostel before the 1 AM overnight bus to Chile.

- Days 3-5
San Pedro de Atacama, Chile
The bus ride takes about 10.5 hours. Once you arrive take the Valle de la Luna tour but remember to pack a windbreaker for the strong afternoon winds. You'll have two more days to explore. Book a stargazing tour for your first night in case of bad weather. If you want to visit the hot springs go early to beat the crowds and the heat.

- Days 6-8
Uyuni Salt Flats Expedition, Bolivia
Get ready for the trip highlight. The quick climb of 2,000 meters means altitude sickness is possible so bring medication. A recent visitor shared: "The altitude hit harder than expected at the geysers – take it slow and drink coca tea when offered." Important items to pack: a good camera that can handle weather, a headlamp and warm clothes for the cold nights. Your three-day tour includes: - Laguna Blanca and Verde - Salvador Dalí Desert - Polques hot springs (bring quick-dry towel) - Morning Sun Geysers - Laguna Colorada - Salt flat photography spots - Incahuasi Island - Train Cemetery

- Day 9
Return to San Pedro
- Day 10
Departure
What people love about 10-day South America tours
- Peru Express - 10 Days (Lima - Cusco - Machu Picchu & Puno) With Domestic Flights
A very good experience I loved the good treatment that is given to the client and that the prices are very accessible, very good quality in terms of this agency, I recommend it.
- Argentina & Bolivia: Salt Flats and Desert
This is really an excellent tour. I loved the city of Salta, the tours around San Pedro de Atacama and, finally, the three journeys in Bolivia ending with the impressive Salar de Uyuni. Do not expect luxuries but the nature is really worth the while. The people from the Say Hueque travel agency were thoughtful and careful about the details
- Brazil and Argentina with Iguazu Falls 4 Star
Very well organized and great activities
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