1-Month+ South America Tour Packages
4.6 stars on(8,517 reviews)- Choose from 50+ South America tours
- 100+ verified reviews from TourRadar travelers
- 24/7 customer support
Insider tips: Recommended 1-month+ South America tour itineraries
Compiled by

NinaSouth America travel expert at TourRadar
35 Day South America Itinerary, incl. Lima and Buenos Aires
South America's iconic landscapes unfold over 35 days, visiting 18 cities. The 4-day Inca Trail leads to Machu Picchu, Lake Titicaca's floating islands welcome visitors, and Salar de Uyuni offers a 3-day expedition. Accommodations vary from camping to community lodges.
- Days 1-2
Lima & Huacachina, Peru
Begin your trip in Lima's colorful Barranco district. "The contrast between modern Lima and the historic center really struck me. Don't miss the sunset over the Pacific from Miraflores cliff walk." On day 2 take a 5-hour bus to Huacachina for sandboarding. Book afternoon sessions when winds are calmer and the sand isn't too hot.
- Days 3-4
Nazca & Arequipa Region
Drive 3 hours to Nazca. You can take an early morning flight over the Nazca Lines if you book ahead. Stop for a traditional pachamanca lunch where meat and vegetables are cooked underground. Take an overnight bus to Arequipa. "The Nazca Lines flight can be bumpy - take motion sickness pills if you're sensitive."
- Days 5-8
Arequipa & Colca Canyon
Visit "The White City" and stunning Colca Canyon. Take a day trip to see Andean condors. Get to Cruz del Condor by 8AM for the best views. "Get to Cruz del Condor viewpoint early before tourist buses arrive." Back in Arequipa you can explore Santa Catalina Monastery and try local spicy rocoto relleno.
- Days 9-15
Cusco & Machu Picchu
Take an overnight bus to Cusco. Spend two days getting used to the altitude before starting the 4-day Inca Trail. Important tip: "Pack light for the trail - porters have strict weight limits. Bring hiking poles for steep descents." Visit the Sacred Valley including a women's weaving cooperative in Ccaccaccollo. The trail ends at Machu Picchu where you can catch sunrise at the Sun Gate.
- Days 16-20
Lake Titicaca & La Paz
- Days 21-27
Sucre, Potosí & Uyuni
- Days 28-31
Atacama & Northern Argentina
- Days 32-35
Final Stretch to Buenos Aires
31 Days in South America, incl. La Paz and Rio de Janeiro
A stunning 31-day route covers 15 South American cities across 5 countries. Three days at Salar de Uyuni, 2 days at Iguazu Falls from both sides, and stays in colonial gems like Sucre and Paraty complement beach time in Ilha Grande.
- Days 1-2
La Paz, Bolivia
At 11,900ft, La Paz requires careful acclimation. Spend your first day on gentle walks around Plaza Murillo and the Witches' Market. "The altitude hit me harder than expected - definitely worth spending that first day just wandering the markets slowly and drinking coca tea," one traveler shared. On day 2, explore more of the city before taking the overnight bus to Sucre (14 hours).
- Days 3-4
Sucre, Bolivia
- Days 5-6
Potosí, Bolivia
- Days 7-10
Uyuni Salt Flats, Bolivia
Most travelers consider this a highlight. Take a 4-hour private transfer to Uyuni, then spend 3 days exploring the salt flats and desert by 4x4. Pack warm clothes for freezing nights. "The salt hotel was surprisingly comfortable, but bring a power bank - electricity only runs certain hours," notes one reviewer.
- Days 11-12
San Pedro de Atacama, Chile
- Days 13-14
Salta, Argentina
39 Day South America Itinerary, incl. Machu Picchu and Rio de Janeiro
South America's diversity shines over 39 days across 15 major destinations. The path leads from Lima through Cusco's ancient streets, across Bolivia's salt flats to Chile's Atacama Desert. Machu Picchu trekking, Amazon jungle exploration, and Iguazu Falls precede the finale in vibrant Rio de Janeiro.
- Days 1-5
Peru's Highlights
Start your journey in Lima. The city's traffic gets heavy from 7-9am and 5-7pm, so plan your airport transfer outside these times. Spend time in the Miraflores district and try local ceviche at San Pedro market. A quick flight takes you to Puerto Maldonado for 2 nights in the Amazon. Pack quick-dry clothes and strong mosquito repellent. The humidity often hits 90%. A recent visitor said: "The jungle lodge was basic but watching caimans on night patrol was unforgettable. Bring a headlamp!"
- Days 6-9
Machu Picchu Trek
You can pick the classic Inca Trail (4 days), Quarry Trail, or take the train. If you're hiking, spend 2 days in Cusco first to adjust to the altitude. Many people get sick above 3,000m. Pack for all weather. Nights can be freezing while days get hot. Dead Woman's Pass (4,215m) is a tough 5-6 hour climb. Book your Machu Picchu permits 6 months early before they run out.
- Days 10-14
Lake Titicaca & La Paz
The morning bus from Cusco to Puno takes 6-7 hours. Visit the floating islands and stay with a local family on Lake Titicaca. Bring warm clothes for the cold nights. Head into Bolivia and take time to adjust in La Paz (3,640m). One traveler noted: "The Witches Market was fascinating but take it slow. The steep streets combined with thin air left me winded."
- Days 15-21
Bolivian Salt Flats to Argentina
- Days 22-32
Buenos Aires & Uruguay
Walk through BA's neighborhoods like San Telmo and La Boca. Take a 1-hour ferry to Colonia del Sacramento, then a 2.5-hour bus to Montevideo. Experience ranch life at an estancia. Get ready for early mornings and simple living. A guest shared: "The homestay was rustic but sharing mate tea with the family was a highlight."
- Days 33-39
Iguazu & Brazil Finale
What people love about 1-month+ South America tours
- Overland Latin America
My first time in South America traveling alone, I was lost between all the different options for the tours online. I came on UnuRaymi’s website by accident and wrote to them on WhatsApp. They were incredibly responsive and took the time to structure the perfect tour for me. Starting at Lima, all the way to Cusco, the rainbow mountain, the amazon jungle and Machu Picchu, I felt very well taken care of and I would recommend them to anyone trying to travel to Peru !
More about South America
10 Best South America Backpacking Tours & Trips 2025/202610 Best Adventure Trips for Couples 2025/202610 Best South America Honeymoon Packages & Tours 2025/202610 Best South America Travel Specialists (with Reviews)Weather in South America in 2025/2026What is the best time to visit South America in 2025/2026?