River Cruises from Siem Reap to Ho Chi Minh City
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10 best River cruises from Siem Reap to Ho Chi Minh City
Compiled by

MelissaSiem Reap travel expert at TourRadar
- From Siem Reap to the Mekong Delta (port-to-port cruise)
- Spiritual Cambodia and The Mekong Siem Reap → Ho Chi Minh City (2025)
- Essential Vietnam and Cambodia Siem Reap to Ho Chi Minh City (2025)
- Treasures of the Mekong 2025-2026|2026-2027 - 13 Days
- Majestic Mekong Cruise Siem Reap → Ho Chi Minh City (2025)
- Enchanting Mekong and Siem Reap 2026 - 11 Days
- Luxury Mekong and Temple Discovery Cruise 2025-2026|2026-2027 - 11 Days
- Mekong River Cruise & Dolphin Encounter 7-Night Cambodia to Vietnam
- Riches of the Mekong 2026
- Riches of the Mekong 2027
From Siem Reap to the Mekong Delta (port-to-port cruise)
1 Review by TourRadar travelers“Comfortable ship. Very nice crew.”
ALEKSANDER, traveled in February
Your 9-day cruise from Lotus Blanc Hotel in Siem Reap reaches Ho Chi Minh City via Tonle Sap Lake. Stop at Kampong Chhnang's pottery villages, Phnom Penh's Silver Pagoda, and navigate the Chao Gao Canal.
Duration 9 days Destinations Siem Reap, Tonle Sap Lake, Kampong Tralach, Koh Chen, Phnom Penh, Chau Doc, Sa Dec, Vinh Long, Cai Be, My ThoSee all destinations Age Range All Ages Welcome Operator CroisiEurope River Cruises From
- NZ$3,953
Witness Angkor Wat's sunrise before boarding Mekong Serenity for 7 nights. The 11-day journey through Kampong Cham, Phnom Penh, and Sa Dec features Buddhist blessings at Oudong monastery and silk weaving demonstrations in Oknha Tey.
Duration 11 days Destinations Siem Reap, Kampong Cham, Koh Pen, Angkor Ban, Phnom Penh, Oudong, Koh Chen, Tan Chau, Sa Dec, Cai BeSee all destinations Age Range Ages 8+ Operator APT From
- NZ$7,814+$793 upfront costs
This 12-day journey from Shinta Mani Angkor includes Ta Prohm and Angkor Wat before a 7-night RV Apsara cruise. Villages like Angkor Ban and Tan Chau dot the route to Ho Chi Minh City's Cu Chi Tunnels and Le Meridien Saigon.
Duration 12 days Destinations Siem Reap, Kampong Cham, Angkor Ban, Phnom Penh, Silk Island, Oudong, Koh Chen, Tan Chau, Sa Dec, Cai BeSee all destinations Age Range Ages 8+ Operator APT From
- NZ$6,431+$816 upfront costs
Duration 13 days Destinations Siem Reap, Hanchey, Kampong Cham, Angkor Ban, Silk Island, Phnom Penh, Tan Chau, Sa Dec, Cai Be, Ho Chi Minh City Age Range Ages 12+ Operator Scenic Luxury Cruises & Tours From $11,685
21% Off- NZ$9,185You save $2,500
A tuk-tuk ride through Koh Pen island starts your 8-day RV Apsara cruise from Siem Reap to Ho Chi Minh City. Visit Angkor Ban's 'Lucky Village', Phnom Penh's Silver Pagoda, and watch traditional silk weaving in Oknha Tey.
Duration 8 days Destinations Siem Reap, Kampong Cham, Angkor Ban, Phnom Penh, Oudong, Koh Chen, Tan Chau, Sa Dec, Cai Be, My ThoSee all destinations Age Range Ages 12+ Operator Travel Marvel From
21% Off- NZ$4,301+$680 upfront costs
Duration 11 days Destinations Siem Reap, Kampong Tralach, Oudong, Phnom Penh, Tan Chau, Cu Lao Gieng, My An Hung, Sa Dec, Cai Be, My ThoSee all destinations Age Range Ages 12+ Operator Emerald Cruises From $20,117
46% Off- NZ$10,833You save $9,284
Duration 11 days Destinations Siem Reap, Hanchey, Kampong Cham, Angkor Ban, Silk Island, Phnom Penh, Tan Chau, Sa Dec, Cai Be, Ho Chi Minh City Age Range Ages 12+ Operator Scenic Luxury Cruises & Tours From $10,590
14% Off- NZ$9,090You save $1,500
Duration 8 days Destinations Siem Reap, Kratie, Kampong Cham, Phnom Penh, My An Hung, Cai Be, Thới Bình, My Tho, Ho Chi Minh City Age Range Ages 12+ Operator Lotus Cruises From
14% Off- NZ$4,455
The luxurious AmaDara awaits in Kampong Cham after departing Siem Reap, sailing through Cambodia's cultural treasures to Vietnam's Mekong Delta. Sa Dec's markets and My Tho Port highlight the journey to Ho Chi Minh City. Seven nights of luxury river cruising showcase regional cuisine.
Duration 8 days Destinations Siem Reap, Kampong Cham, Angkor Ban, Oudong, Phnom Penh, Tan Chau, Sa Dec, My Tho, Ho Chi Minh City Age Range Ages 12+ Operator AmaWaterways From
14% Off- NZ$4,989+$430 upfront costs
A 7-night voyage aboard AmaDara connects Siem Reap to Ho Chi Minh City via Kampong Cham. The 315-mile route encompasses 11 destinations, including Angkor Ban's preserved villages, Phnom Penh's Royal Palace, and Oudong's monasteries.
Duration 8 days Destinations Siem Reap, Kampong Cham, Angkor Ban, Silk Island, Phnom Penh, Oudong, Tan Chau, Mekong Delta, Sa Dec, My ThoSee all destinations Age Range Ages 12+ Operator AmaWaterways From
14% Off- NZ$5,161+$482 upfront costs
What people love about River Cruise Tours from Siem Reap to Ho Chi Minh City
- 7-night Mekong Downstream Cambodia Vietnam on Mekong Navigator
Staff excellent. Cabin lovely but situated back of boat and engine noise so loud prevented sleep. Other passengers were warned if this and given a reduced rate. Food and service excellent. Mooring at Phnom Penh for three nights with no view but underside of dock made balcony unusable for almost half of cruise. €1000 refund from Lotus accepted. Tourradar attempt to claim 20% of that disgraceful.
What our customers ask about River Cruises from Siem Reap to Ho Chi Minh City
What are the key stops and highlights between Siem Reap and Ho Chi Minh City on these river cruises?
Your journey starts near Siem Reap at Angkor Wat and Tonle Sap Lake, then takes you down the Mekong River. In Cambodia, you'll stop at the fishing port of Kampong Chhnang and visit Koh Chen, where local families craft beautiful silverware. The cruise continues to Phnom Penh, where you can explore the Royal Palace and Silver Pagoda. Once in Vietnam, you'll experience the lively floating markets of Chau Doc, wander through Sa Dec's French colonial streets, and watch artisans at work in traditional workshops in Cai Be. As one TourRadar traveler said, "the variety of stops and cultural experiences along the Mekong make this journey truly memorable."
What is the typical duration of a river cruise from Siem Reap to Ho Chi Minh City?
Most cruises last between 8 and 13 days, with many taking 11 or 12 days to complete the journey. For example, if you take the CroisiEurope cruise on the RV Indochine II, you'll spend 11 days visiting places like Angkor Wat, Phnom Penh, and small villages along the Mekong. One TourRadar traveler mentioned, "We had a great time exploring multiple destinations though some activities were repetitive, especially the pagoda visits."
How much does a river cruise from Siem Reap to Ho Chi Minh City typically cost?
You'll find prices starting at USD 2,660 and going up to USD 14,635 per person. If you want a luxury experience with a company like Scenic Luxury Cruises, expect to pay between USD 12,000 and USD 14,000. For a mid-range option, companies like CroisiEurope offer cruises starting around USD 3,900. These prices usually cover your room, food, guided tours, and activities on the ship.
What is the best time of year to take a river cruise from Siem Reap to Ho Chi Minh City?
Most people take these cruises during the dry season from October through February. December and January are especially popular because the weather is nice with less humidity and temperatures between 77-86°F (25-30°C). September and March work too, but you might see some rain. Not many cruises run from June through August because it's hot and wet, with temperatures getting up to 95°F (35°C).
What kind of cultural experiences and activities are included in these river cruises?
You'll get to know local life through village visits, market tours, and temple explorations. In Phnom Penh, you can watch traditional Apsara dancers perform. You'll meet silversmiths in Koh Chen, browse floating markets, and take small boat rides through narrow canals. Many cruises include cooking classes where you'll learn to make Vietnamese dishes, and you'll see how local craftspeople make traditional products. One TourRadar traveler shared, "the combination of cultural shows, local craft demonstrations, and village visits provided an authentic insight into life along the Mekong."